60 year old man with chronic cardiac failure

on Friday, July 22, 2022

 


A 60 year old man with chronic cardiac failure is on treatment with digoxin and a loop diuretic.

This combination is likely to cause digoxin toxicity by the following mechanism?


a) this combination increases the half-life of digoxin

b) diuretics decrease potassium levels

c) frusemide and digoxin interact to form a poisonous compound

d) digoxin is a competitive inhibitor of frusemide

e) the above statement is wrong, loop diuretics are not a recognized cause of increased digoxin toxicity

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