A child with anemia

Question Number 1169

A child with anemia has a sample of red blood cells tested against varying concentrations of a hypotonic solution of sodium chloride. The same test is also performed after incubation of the blood overnight.
The likely cause of the patient's anemia is:

a) Hemoglobin E
b) hemoglobin S
c) hemophilia
d) thalassemia
e) spheroctosis

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