UKMLA PLAB AMC USMLE Prometric MCQ

Question Number 0519

Question:
A 7 year old is noted to have mild icterus. On examination he is found to have moderate splenomegaly. Investigations reveal a conjugated hyperbilirubinemia. There are normal levels of AST, ALT, albumin, alkaline phosphatase. Tests on the urine reveal an elevated total coproporphyrin excretion of 5 times the normal with 25% being coproporphyrin I. A liver biopsy is normal. A likely diagnosis is

a) Rotor's Syndrome
b) primary biliary cirrhosis
c) Gilbert's Syndrome
d) hepatitis B
e) hemolysis