ANSWER :PAEDIATRIC MCQ 2:A term newborn infant is noticed to be hypotonic



2) A term newborn infant is noticed to be hypotonic. The following are possible causes:


Causes of neonatal hypotonia can be classified anatomically: Systemic: sepsis, trisomies,
metabolic disease, e.g. galactosaemia, drugs, etc Brain: hypoxic ischaemic encephalopathy,
intracranial haemorrhage, malformations Spinal cord: birth trauma, spina bifida, tumour
Anterior horn cell: spinal muscular atrophy Neuromuscular junction: neonatal myasthenia
gravis Muscle: congenital myopathies, benign congenital hypotonia.


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