Answer:USMLE step 2 Mcq 193:A 23 year old female presented to the emergency department with pallor and hemoptysis





Correct Answer: D

In this case the presence of her pulmonary hemorrhage, glomerulonephritis, and positive anti-basement membrane serology,diagnosis of Goodpasture's syndrome is made. Goopasture's syndrome is now defined as a triad of: a) pulmonary or alveolar hemorrhage (defined as hemoptysis, unexplained anemia, and diffuse alveolar infiltrates on chest x-ray) (2), b) glomerulonephritis (cresentic or rapidly progressive), and c) serum anti-basement membrane antibodies or linear immunofluorescence of IgG on basement membranes. Death in Goodpasture's disease is usually secondary to chronic renal failure


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