Answer :USMLE step 2 Mcq 261:An immuno-competent patient develops diarrhea




Correct Answer: E

Look at the brush border, there are several small spores<br>Once believed not to be a pathogen in humans, these little creatures live in the brush border of the gut and are an important cause of diarrhea worldwide. In people who are immunocompromised, it can be hard to shake the infection  The most widely used diagnostic test is the modified acid-fast or Kinyoun stain. It is used to detect Cryptosporidium in stool samples. Several immunofluorescent assays are also available, which test for antibodies to the parasite in the blood. Some pharmaceutical companies have produced rapid-result commercial assays, which are moderately successful (~75% detection rate). Polymerase chain reaction (PCR) techniques might also prove to be effective in diagnosing infection.  Treatment usually is not required for cryptosporidiosis in patients who are immunocompetent, and no clinical trials have convincingly demonstrated the efficacy of antimicrobics.


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