Answer :USMLE step 2 Mcq 251:Researchers want to conduct a study of the effect of early detection on prognosis in patients with lung cancer

on Thursday, December 16, 2010

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Correct Answer: C

Explanation:
Lead time bias is caused by a comparison between screening-detected cases and others which overestimates benefit because the former consists of cases that were diagnosed earlier, progress more slowly, and may never become clinically relevant.

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